Synthetic nanoscale electrostatic particles as growth factor carriers for cartilage repair
نویسندگان
چکیده
منابع مشابه
Synthetic nanoscale electrostatic particles as growth factor carriers for cartilage repair
The efficient transport of biological therapeutic materials to target tissues within the body is critical to their efficacy. In cartilage tissue, the lack of blood vessels prevents the entry of systemically administered drugs at therapeutic levels. Within the articulating joint complex, the dense and highly charged extracellular matrix (ECM) hinders the transport of locally administered therape...
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A growth factor-based strategy recently has been shown to induce the intrinsic repair of partial-thickness articular cartilage lesions, thereby obviating the need for transplanting cells or tissue. It was the purpose of the current study to ascertain whether this principle could be applied to full-thickness articular cartilage defects created in adult rabbits and mature miniature pigs. The tran...
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ژورنال
عنوان ژورنال: Bioengineering & Translational Medicine
سال: 2016
ISSN: 2380-6761,2380-6761
DOI: 10.1002/btm2.10043